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A case of intracytoplasmic edema of follicular epithelial cells in rat thyroid.

Authors
  • Takaoka, M
  • Yamoto, T
  • Teranishi, M
  • Manabe, S
  • Goto, N
Type
Published Article
Journal
The Journal of veterinary medical science / the Japanese Society of Veterinary Science
Publication Date
Oct 01, 1994
Volume
56
Issue
5
Pages
989–991
Identifiers
PMID: 7865607
Source
Medline
License
Unknown

Abstract

Hydropic change of follicular epithelial cells in the thyroid was observed in a female Fischer 344 rat. Microscopically follicular epithelial cells were characterized by edematous swelling with weakly eosinophilic and homogeneous cytoplasm. The cytoplasm was negative for periodic acid-Schiff reaction, and thyroxine- and thyroglobulin-immunohistochemical reactions. Electron-microscopically, a small amount of amorphous substance was noted in remarkably dilated rough-surfaced endoplasmic reticulum (r-ER), and slight regressive changes of cytoplasmic organella were also observed. These morphological changes may indicate that focal intracytoplasmic edema was occurred in r-ER, and that the change belonged to hydropic degeneration of the thyroid follicular cells in the thyroid.

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