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A Case of Diffuse Astrocytoma with 32-year Survival after Boron Neutron Capture Therapy.

Authors
  • Kamano, Shuji1
  • Matsuyama, Masayuki1
  • Minamimura, Kenzo2
  • 1 Department of Neurosurgery, Inagi Municipal Hospital, Inagi, Tokyo, Japan. , (Japan)
  • 2 Department of Neurosurgery, Shinkawabashi Hospital, Kawasaki, Kanagawa, Japan. , (Japan)
Type
Published Article
Journal
NMC case report journal
Publication Date
Sep 01, 2020
Volume
7
Issue
4
Pages
211–215
Identifiers
DOI: 10.2176/nmccrj.cr.2019-0228
PMID: 33062571
Source
Medline
Keywords
Language
English
License
Unknown

Abstract

A 39-year-old man had received boron neutron capture therapy (BNCT) for a grade II astrocytoma (compatible with diffuse astrocytoma, not otherwise specified in the WHO 2016 criteria). He returned to his previous work after surgery, but, 7 years later, he suddenly developed seizures, and his health condition deteriorated. Therefore, he underwent a second surgery. The mass removed in the second operation was mostly necrotic as a result of previous radiation treatment. He then showed no signs of recurrence and did not require any treatment other than antiepileptic drugs for 25 years. He was able to be employed by a listed company until the age of 65 years for light jobs as a physically handicapped individual. This case suggests the effectiveness of BNCT even for rather low-grade astrocytomas. © 2020 The Japan Neurosurgical Society.

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