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Carrier-mediated delivery of peptidic drugs for cancer therapy.

Authors
  • Dass, Crispin R
  • Choong, Peter F M
Type
Published Article
Journal
Peptides
Publisher
Elsevier
Publication Date
Nov 01, 2006
Volume
27
Issue
11
Pages
3020–3028
Identifiers
PMID: 16793175
Source
Medline
License
Unknown

Abstract

Protein and peptide drugs are used for treatment of a variety of ailments. However, their wider use has been hindered by issues such as poor bioavailability in vivo and the cost involved in producing these drugs. This review discusses the various carrier-mediated methods used for delivery of peptide and protein drugs, with emphasis on liposomal and microspherical drug delivery systems. A brief look at the types of peptidic drugs currently in use clinically, and a brief discourse on several novel ideas for better protein delivery systems for cancer therapy is included.

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