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Cardiovascular Modulating Effects of Magnolol and Honokiol, two polyphenolic compounds from Traditional Chinese Medicine-Magnolia officinalis.

Authors
  • Yuan, Yuan1
  • Zhou, Xiaocui2
  • Wang, Yuanyuan2
  • Wang, Yan2
  • Teng, Xiangyan2
  • Wang, Shuaiyu1
  • 1 College of Veterinary Medicine, China Agricultural University, Beijing 100193. China. , (China)
  • 2 China Animal Health and Epidemiology Center, Qingdao 266032. China. , (China)
Type
Published Article
Journal
Current drug targets
Publication Date
Oct 24, 2019
Identifiers
DOI: 10.2174/1389450120666191024175727
PMID: 31749425
Source
Medline
Keywords
Language
English
License
Unknown

Abstract

Honokiol and its isomer magnolol are poly-phenolic compounds isolated from the Magnolia officinalis that exert cardiovascular modulating effects via a variety of mechanisms. They are used as a blood-quickening and stasis-dispelling agents in Traditional Chinese Medicine and confirmed to have therapeutic potential in atherosclerosis, thrombosis, hypertension, and cardiac hypertrophy. This comprehensive review summarizes the current date regarding the cardioprotective mechanisms of those compounds and identifies areas for further research. Copyright© Bentham Science Publishers; For any queries, please email at [email protected]

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