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Cardiovascular effects of treatment with taxanes.

Authors
Type
Published Article
Journal
Journal of cardiovascular medicine (Hagerstown, Md.)
Publication Date
Volume
13
Issue
5
Pages
319–324
Identifiers
DOI: 10.2459/JCM.0b013e3283529060
PMID: 22476001
Source
Medline

Abstract

Taxanes are cytotoxic drugs that stabilize cellular microtubules and are among the most active of the antineoplastic agents being widely used in the treatment of cancer patients. Furthermore, taxanes comprise a valuable tool in interventional cardiology. Following treatment with taxanes, in many patients, the risk of cardiovascular complications has recently been noted. This review examines the cardiac toxicity of treatment with taxanes and their use in cardiology and analyzes issues in clinical practice.

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