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[Cardioprotection of ramipril and BQ-123 against myocardial ischemia/reperfusion injury in vivo in rats].

Authors
  • Wang, Yao
  • Huang, Zhuo-Jun
  • Song, Jun-Qiu
  • Wu, Yan-Na
  • Liu, Yan-Xia
Type
Published Article
Journal
Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology
Publication Date
Nov 01, 2009
Volume
25
Issue
4
Pages
478–482
Identifiers
PMID: 21158037
Source
Medline
License
Unknown

Abstract

Ramipril, BQ-123 and combined using these two agents protected myocardium from I/R injury in vivo. The protective effects on delaying onset of VA, shortening duration of VA, decreasing the activities of CK and LDH, decreasing infrarct size and improving morphology of myocardium were better than using ramipril and BQ-123 alone.

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