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[Cardiac and vascular reactions provoked by 5-HT in rats].

Authors
Type
Published Article
Journal
Archives internationales de physiologie et de biochimie
Publication Date
Volume
85
Issue
5
Pages
877–889
Identifiers
PMID: 79368
Source
Medline
License
Unknown

Abstract

In normal rat, anaesthetized with pentobarbital, 5-HT, injected or perfused by intravenous route, provokes different types of cardiovascular responses. These variations are due to the activation of three classes of receptors. The first ones explain the fall of the arterial blood pressure: they are located on arterioles which are dilatated. The second one are para- or perivascular nervous receptors: when stimulated, they induce vago-vagal reflexes (Bezold-Jarisch reflexes) suppressed by vagotomy. The third ones are vasoconstrictor and located on arterioles.

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