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Cardiac troponin I release after severe scorpion envenoming by Tityus serrulatus.

Authors
  • Cupo, Palmira
  • Hering, Sylvia Evelyn
Type
Published Article
Journal
Toxicon
Publisher
Elsevier
Publication Date
Jun 01, 2002
Volume
40
Issue
6
Pages
823–830
Identifiers
PMID: 12175620
Source
Medline
License
Unknown

Abstract

Eight children aged 2-9 years, with signs and symptoms of severe scorpion envenoming by Tityus serrulatus were studied. All patients showed clinical manifestations of cardiac dysfunction, with ECG and echocardiographic alteration and five developed pulmonary edema. Troponin I levels were normal in all patients on admission, except for two who arrived later, and increased thereafter, with maximum values being observed 24-36 h after the sting. The detection of TnI in patients with severe scorpion envenoming, and the observed temporal pattern and serum levels meet the criteria established for the diagnosis of acute myocardial infarction. The rapid reversibility of cardiac dysfunction, together with the normalization of the enzymatic, ECG and echocardiographic data, indicates the occurrence of an acute myocardial lesion without underlying or associated coronary disease.

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