Affordable Access

deepdyve-link
Publisher Website

Carbon nanotubes in cancer therapy: a more precise look at the role of carbon nanotube-polymer interactions.

Authors
  • Adeli, Mohsen
  • Soleyman, Rouhollah
  • Beiranvand, Zahra
  • Madani, Fahimeh
Type
Published Article
Journal
Chemical Society reviews
Publication Date
Jun 21, 2013
Volume
42
Issue
12
Pages
5231–5256
Identifiers
DOI: 10.1039/c3cs35431h
PMID: 23443245
Source
Medline
License
Unknown

Abstract

Despite the great potential of carbon nanotubes (CNTs) in various areas of biomedicine, concerns regarding their carcinogenicity, inefficient dispersion in aqueous solutions and biological activity in vivo still remain. One important and feasible route to overcome these barriers is modification of CNTs with polymers, which are widely studied and play a vital role in biological and biomedical fields, especially in drug delivery. This comprehensive review focuses on the achievements of our and other groups in currently used methods to functionalize the surface of CNTs with polymers to produce anticancer drug delivery systems. We have intensively studied covalent and noncovalent interactions between CNTs and linear, dendritic and hyperbranched biocompatible polymers as well as biomacromolecules interactions which are very crucial to diminish the toxicity of CNTs via changing their conformations.

Report this publication

Statistics

Seen <100 times