Affordable Access

[Carbohydrates in the liver microsome fraction of rats with hypovitaminosis A].

Authors
  • Pentiuk, A A
  • Lutsiuk, N B
  • Gutsol, V I
Type
Published Article
Journal
Ukrainskiĭ biokhimicheskiĭ zhurnal (1978)
Publication Date
Jan 01, 1986
Volume
58
Issue
4
Pages
46–50
Identifiers
PMID: 3739031
Source
Medline
License
Unknown

Abstract

Accessibility for trypsin and sodium deoxycholate was determined in carbohydrates of glycoproteins in the liver microsome fraction of rats, which were kept for 80 days on retinol-deficient diet and received optimal amounts of vitamin A. It was found that the prevailing amount of hexose- and glucosamine-containing glycoproteins is located on the outer surface of membrane vesicles and only a smaller part of these proteins is submerged into the lipid layer of the membrane or is located on its inner surface. Above a half of protein bound with fucose and neuraminic acid is located in the lipid layer. Retinol deficiency leads to translocation of a portion of fucose- and hexose-containing proteins on the outer surface of vesicles and to a decrease of the share of these proteins in the hydrophobic membrane zone.

Report this publication

Statistics

Seen <100 times