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Carbohydrate-based switch-on molecular sensor for Cu(II) in buffer: absorption and fluorescence study of the selective recognition of Cu(II) ions by galactosyl derivatives in HEPES buffer.

Authors
  • Singhal, Nitin Kumar
  • Ramanujam, Balaji
  • Mariappanadar, Vairamani
  • Rao, Chebrolu Pulla
Type
Published Article
Journal
Organic Letters
Publisher
American Chemical Society
Publication Date
Aug 03, 2006
Volume
8
Issue
16
Pages
3525–3528
Identifiers
PMID: 16869651
Source
Medline
License
Unknown

Abstract

[graph: see text] 1-(Beta-D-galactopyranosyl-1'-deoxy-1'-iminomethyl)-2-hydroxynaphthalene (L1), possessing an ONO binding core, was found to be selective for Cu2+ ions in N-[2-hydroxyethyl]piperazine-N'-[2-ethanesulfonic acid] buffer, at concentrations < or = 580 ppb, at physiological pH by eliciting switch-on behavior, whereas the other ions, viz., Mg2+, Ca2+, Mn2+, Fe2+, Co2+, Ni2+, Zn2+, and Cd2+, caused no significant change in the fluorescence. Whereas the binding characteristics were ascertained by absorption spectroscopy, the species formed were shown by Q-TOF ES MS.

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