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CAR: three new models for a problem child.

Authors
  • Moore, David D
Type
Published Article
Journal
Cell Metabolism
Publisher
Elsevier
Publication Date
Jan 01, 2005
Volume
1
Issue
1
Pages
6–8
Identifiers
PMID: 16054039
Source
Medline
License
Unknown

Abstract

By comparison with its older and better-behaved cousins in the nuclear receptor superfamily, CAR (NR1I3) has always been an oddball. Three new crystal structures recently described in Molecular Cell reveal the molecular basis for some of its bad habits (Xu et al., 2004; Suino et al., 2004; Shan et al., 2004).

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