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Capture of circulatory endothelial progenitor cells and accelerated re-endothelialization of a bio-engineered stent in human ex vivo shunt and rabbit denudation model.

Authors
  • Larsen, Katarína1
  • Cheng, Caroline
  • Tempel, Dennie
  • Parker, Sherry
  • Yazdani, Saami
  • den Dekker, Wijnand K
  • Houtgraaf, Jaco H
  • de Jong, Renate
  • Swager-ten Hoor, Stijn
  • Ligtenberg, Erik
  • Hanson, Stephen R
  • Rowland, Steve
  • Kolodgie, Frank
  • Serruys, Patrick W
  • Virmani, Renu
  • Duckers, Henricus J
  • 1 Molecular Cardiology Laboratory, Ee2389a, Experimental Cardiology, Thoraxcenter, Erasmus University Medical Center, 's-Gravendijkwal 230, 3015 GE Rotterdam, The Netherlands.
Type
Published Article
Journal
European Heart Journal
Publisher
Oxford University Press
Publication Date
January 2012
Volume
33
Issue
1
Pages
120–128
Identifiers
DOI: 10.1093/eurheartj/ehr196
PMID: 21733913
Source
Medline
License
Unknown

Abstract

In this proof-of-concept study, we have demonstrated that the bio-engineered EPC-capture stent, Genous™ R™ stent, is effective in EPC capture, resulting in accelerated re-endothelialization and reduced thrombogenicity.

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