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The capacity of testicular cells of the postnatal rat to reorganize into histotypic structures.

Authors
  • Zenzes, M T
  • Engel, W
Type
Published Article
Journal
Differentiation; research in biological diversity
Publication Date
Jan 01, 1981
Volume
20
Issue
2
Pages
157–161
Identifiers
PMID: 7327316
Source
Medline
License
Unknown

Abstract

Cell reorganization experiments in vitro were performed with dissociated rat testes at different ages of postnatal development namely, newborn, 8-10, 18-25, 35-40, and 90 days. Only newborn and juvenile rat testicular cells reassociated into testicular-like organization in rotation culture. Puberal and adult rat testicular cells show morphogenetic organization when they were deprived or germ cells by busulphan pretreatment. A factor present in testicular tissue of puberal and adult rats inhibits reorganization. The inhibitor is confined to the spermatic cell fraction in the testis.

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