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Cannabis Use Is Associated With Increased Risk for Diabetic Ketoacidosis in Adults With Type 1 Diabetes: Findings From the T1D Exchange Clinic Registry.

Authors
  • Kinney, Gregory L1
  • Akturk, Halis K2
  • Taylor, Daniel D3
  • Foster, Nicole C4
  • Shah, Viral N2
  • 1 Colorado School of Public Health, University of Colorado Anschutz Medical Campus, Aurora, CO [email protected]
  • 2 Barbara Davis Center for Diabetes, University of Colorado Anschutz Medical Campus, Aurora, CO.
  • 3 Colorado School of Public Health, University of Colorado Anschutz Medical Campus, Aurora, CO.
  • 4 Jaeb Center for Health Research, Tampa, FL.
Type
Published Article
Journal
Diabetes care
Publication Date
Oct 18, 2019
Identifiers
DOI: 10.2337/dc19-0365
PMID: 31628116
Source
Medline
Language
English
License
Unknown

Abstract

We examined the frequency of diabetic ketoacidosis (DKA) in cannabis users compared with nonusers in the T1D Exchange clinic registry (T1DX). The association between cannabis use by total substance score for cannabis (TSC) and DKA in the past 12 months was examined using a logistic regression model adjusted for potential confounders among adults in the T1DX. Of 932 adults with type 1 diabetes, 61 had a TSC >4, which classified them as moderate cannabis users. Adjusting for sex, age at study visit, and HbA1c, cannabis use was associated with a two-fold increase in risk for DKA among adults with type 1 diabetes (odds ratio 2.5 [95% CI 1.0-5.9]). Cannabis use was associated with an increased risk for DKA among adults in the T1DX. Providers should inform their patients of the potential risk of DKA with cannabis use. © 2019 by the American Diabetes Association.

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