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Is cannabis neurotoxic for the healthy brain? A meta-analytical review of structural brain alterations in non-psychotic users.

Authors
  • Rocchetti, Matteo
  • Crescini, Alessandra
  • Borgwardt, Stefan
  • Caverzasi, Edgardo
  • Politi, Pierluigi
  • Atakan, Zerrin
  • Fusar-Poli, Paolo
Type
Published Article
Journal
Psychiatry and Clinical Neurosciences
Publisher
Wiley (Blackwell Publishing)
Publication Date
Nov 01, 2013
Volume
67
Issue
7
Pages
483–492
Identifiers
DOI: 10.1111/pcn.12085
PMID: 24118193
Source
Medline
Keywords
License
Unknown

Abstract

Our results suggest that in the healthy brain, chronic and long-term cannabis exposure may exert significant effects in brain areas enriched with cannabinoid receptors, such as the hippocampus, which could be related to a neurotoxic action.

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