Affordable Access

Access to the full text

“Camel nanoantibody” is an efficient tool for research, diagnostics and therapy

Authors
  • Tillib, S. V.1
  • 1 Institute of Gene Biology of the Russian Academy of Sciences, ul. Vavilova 34/5, Moscow, 119334, Russia , Moscow (Russia)
Type
Published Article
Journal
Molecular Biology
Publisher
Pleiades Publishing
Publication Date
Feb 22, 2011
Volume
45
Issue
1
Pages
66–73
Identifiers
DOI: 10.1134/S0026893311010134
Source
Springer Nature
Keywords
License
Yellow

Abstract

This short review provides an introduction to the rapidly developing field of generation and utilization of “camel nanoantibodies” (or “nanobodies”). The term “nanoantibody” or “nanobody” was given to single-domain variable fragments of special type of antibodies that naturally exist (in addition to classical types of antibodies) in blood of Camelidae family animals and in some chondrichthyan fishes. The existence of very efficient technology of nanobody generation and some very useful characteristic features promise a big potential for their use in immunobiotechnology and medicine.

Report this publication

Statistics

Seen <100 times