The minimum energy conformations of the four sterically reasonable SLe(x) and SLe(a) lactones were calculated using the molecular mechanics force-field MM2(91). The tetrasaccharide lactone involving the 3- and 2-position of the Gal moiety was found to be more stable than the 3,4-lactone both for SLe(x) and SLe(a).
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The corresponding record at NLM can be accessed at https://www.ncbi.nlm.nih.gov/pubmed/7757422