Affordable Access

Calculated conformations of sialyl-Le(x)- and sialyl-Le(a)-lactones.

Authors
  • Ellervik, U
  • Magnusson, G
Type
Published Article
Journal
Bioorganic & Medicinal Chemistry
Publisher
Elsevier
Publication Date
Nov 01, 1994
Volume
2
Issue
11
Pages
1261–1266
Identifiers
PMID: 7757422
Source
Medline
License
Unknown

Abstract

The minimum energy conformations of the four sterically reasonable SLe(x) and SLe(a) lactones were calculated using the molecular mechanics force-field MM2(91). The tetrasaccharide lactone involving the 3- and 2-position of the Gal moiety was found to be more stable than the 3,4-lactone both for SLe(x) and SLe(a).

Report this publication

Statistics

Seen <100 times