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[Calcium metabolism in arterial hypertension. I. Myocardial hypertrophy and hormone-dependent increase in Ca2+ levels in the thrombocytes of patients with arterial hypertension].

Authors
Type
Published Article
Journal
Biulleten' Vsesoiuznogo kardiologicheskogo nauchnogo tsentra AMN SSSR
Publication Date
Volume
11
Issue
1
Pages
23–27
Identifiers
PMID: 2969736
Source
Medline

Abstract

Clonidine-treated patients with essential hypertension demonstrated reliable positive correlations between echocardiographically determined signs of myocardial hypertrophy (thickness of left ventricular posterior wall and interventricular septum, left ventricular myocardial mass) and hormone-dependent increase in thrombocyte calcium concentration induced by ADP and TAF. Antihypertensive therapy was more effective in patients with relatively weak cellular effect of Ca-increasing hormone response having no signs of myocardial hypertrophy.

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