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Calcium channel blockers for acute traumatic brain injury.

Authors
  • Langham, J
  • Goldfrad, C
  • Teasdale, G
  • Shaw, D
  • Rowan, K
Type
Published Article
Journal
The Cochrane database of systematic reviews
Publication Date
Jan 01, 2003
Issue
4
Identifiers
PMID: 14583925
Source
Medline
License
Unknown

Abstract

This systematic review of randomised controlled trials of calcium channel blockers in acute traumatic head injury patients shows that considerable uncertainty remains over their effects. The effect of nimodipine in a subgroup of brain injury patients with subarachnoid haemorrhage shows a beneficial effect, though the increase in adverse reactions suffered by the intervention group may mean that the drug is harmful for some patients.

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