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Caffeine versus theophylline for apnea in preterm infants.

Authors
  • Henderson-Smart, David J
  • Steer, Peter A
Type
Published Article
Journal
The Cochrane database of systematic reviews
Publication Date
Jan 01, 2010
Issue
1
Identifiers
DOI: 10.1002/14651858.CD000273.pub2
PMID: 20091506
Source
Medline
License
Unknown

Abstract

Caffeine appears to have similar short-term effects on apnea/bradycardia as does theophylline although caffeine has certain therapeutic advantages over theophylline. Theophylline is associated with higher rates of toxicity. The possibility that higher doses of caffeine might be more effective in extremely preterm infants needs further evaluation in randomized clinical trials.

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