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Caerulein and cholecystokinin reverse experimental hemorrhagic shock.

Authors
  • Bertolini, A
  • Guarini, S
  • Ferrari, W
  • Rompianesi, E
Type
Published Article
Journal
Neuropeptides
Publication Date
Jul 01, 1986
Volume
8
Issue
1
Pages
25–31
Identifiers
PMID: 3762876
Source
Medline
License
Unknown

Abstract

Intravenously injected cholecystokinin octapeptide (CCK-8) (5-20/micrograms/kg) and caerulein (1.25-10/micrograms/kg) caused a prompt, dose-dependent and sustained improvement in blood pressure, pulse amplitude and survival in rats subjected to otherwise invariably fatal hemorrhagic shock.

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