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Caenorhabditis elegans.

Authors
  • Wixon, J
  • Blaxter, M
  • Hope, I
  • Barstead, R
  • Kim, S
Type
Published Article
Journal
Yeast (Chichester, England)
Publication Date
Apr 01, 2000
Volume
17
Issue
1
Pages
37–42
Identifiers
PMID: 10797600
Source
Medline
License
Unknown

Abstract

Transparent, free-living nematode worm. Unsegmented body plan with full set of differentiated tissues (neural, endoderm, ectoderm and muscle). Genome size approximately 97 Mb, as five autosomes and one X sex chromosome. Fully sequenced genome, which comprises approximately 20 000 predicted genes. Defined cell lineage. Has made major contribution to studies of development, cell-to-cell signalling, cell ageing and cell death processes. Large-scale gene deletion, microarray analysis of gene expression and two-hybrid protein interaction analysis projects under way. Comparative studies mainly with C. briggsae, but also with other free-living and parasitic nematodes.

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