Affordable Access

Publisher Website

Ultrasound Elastography of Ethanol-induced Hepatic Lesions:In VitroStudy

Authors
Journal
Chinese Medical Sciences Journal
1001-9294
Publisher
Elsevier
Publication Date
Volume
24
Issue
2
Identifiers
DOI: 10.1016/s1001-9294(09)60065-1
Keywords
  • Elastography
  • Ultrasound
  • Hepatic Cirrhosis
  • Ethanol
Disciplines
  • Biology
  • Medicine
  • Musicology
  • Physics

Abstract

Objective To study the value of ultrasound elastography in evaluation of ethanol-induced lesions of liver. Methods Alcohol with a dose of 2 ml was injected into a fresh porcine liver under ultrasound guidance to create stiff necrosis. Then freehand elastography of the lesion from the identical scan plane was obtained with SONOLINE Antares system using VF10-5 probe at about every 30 seconds till 6 minutes later. The original high quality radiofrequency data were acquired through an ultrasound research interface which was provided by the ultrasound system. Then, corresponding elastograms were produced offline using cross-correlation technique and compared with gross pathology findings. Results Gray-scale sonogram showed a hyperechoic area with acoustic shadow below appeared immediately after alcohol injection. The hyperechoic area tended to be diffuse and its boundary to be illegible with time. On the contrary, the ethanol-induced lesion in elastogram appeared as a low strain hard region surrounded by high strain soft hepatic tissues, with clear but irregular boundaries. Sequential elastograms with the sketched lesion boundaries showed that the lesion area increased in the first 3 minutes after ethanol injection, and then reached a plateau which corresponding to gross specimen. Conclusion Ultrasound elastography is capable of detecting and evaluating the diffusion of ethanol-induced hepatic lesion, and more sensitive and accurate than routine sonography.

There are no comments yet on this publication. Be the first to share your thoughts.

Statistics

Seen <100 times
0 Comments

More articles like this

[Ultrasound elastography of ethanol-induced hepati...

on Zhongguo yi xue ke xue yuan xu... December 2008

Ultrasound elastography of ethanol-induced hepatic...

on Chinese Medical Sciences Journ... June 2009

Ultrasound Elastography of Breast Lesions

on Ultrasound Clinics Jan 01, 2011

In vivo elastographic investigation of ethanol-ind...

on Ultrasound in Medicine & Biolo... May 2005
More articles like this..