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Short and unexpectedly potent difluorostatone type inhibitors of HIV-1 protease

Authors
Journal
Bioorganic & Medicinal Chemistry Letters
0960-894X
Publisher
Elsevier
Publication Date
Volume
3
Issue
2
Identifiers
DOI: 10.1016/s0960-894x(01)80887-8

Abstract

Difluorostatone type derivatives of limited size have been identified as potent inhibitors of HIV-1 protease through structure activity relationship and concept evaluation studies.

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