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Effects of neonatal food deprivation on cortical spines and dendritic development of the rat

Authors
Journal
Brain Research
0006-8993
Publisher
Elsevier
Publication Date
Volume
73
Issue
1
Identifiers
DOI: 10.1016/0006-8993(74)91012-9
Disciplines
  • Biology

Abstract

Abstract The large cortical pyramidal cells of layer V of the frontal and occipital areas have been examined with Golgi staining in normal and malnourished infant rats. The number of spines, the basilar dendritic density and the dendritic thickness were significantly reduced in the group of starved rats. The functional significance of these findings is discussed in relation to other morphological and electrophysiological changes in cortical structures, and their possible implications upon the physiological integrative processes of the CNS at later ages in life.

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