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Surfactant driven flows overlying a hydrophobic epithelium: film rupture in the presence of slip

Authors
Journal
Journal of Colloid and Interface Science
0021-9797
Publisher
Elsevier
Publication Date
Volume
264
Issue
1
Identifiers
DOI: 10.1016/s0021-9797(03)00449-1
Keywords
  • Monolayers And Thin Films
Disciplines
  • Biology
  • Medicine

Abstract

Abstract Both for tear films and along the airways within the lung, one has an extremely thin fluid layer overlying a biological substrate; in both cases surfactants either of natural origin, or artificially introduced, are important in driving fluid flows. There is evidence that slip can occur when hydrophilic liquids, similar to mucus or aqueous tear films, overlie hydrophobic epithelium. Utilizing results from recent experimental findings we examine the possible influence of slip upon tear film rupture, important in so-called dry eye, and upon surfactant-induced flows within the lung, used in surfactant replacement therapy.

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