Graphical abstract The synthesis of anionic amido/carbocyclic carbene ligated Pd (II) complex has been reported. The palladium complex is an active catalyst for the cross-coupling reaction between aryl and phenylboronic acids under phosphine-free conditions at room temperature. Highlights ► Synthesis of multi-functional and multi-donor ligand from amino alcohol. ► Preparation of stable anionic amido/carbocyclic carbene ligated Pd (II) complex. ► Highly efficient catalysts for Suzuki reaction of deactivated aryl bromides and iodides.