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CHRD, a novel domain in the BMP inhibitor chordin, is also found in microbial proteins

Authors
Journal
Trends in Biochemical Sciences
0968-0004
Publisher
Elsevier
Publication Date
Volume
28
Issue
9
Identifiers
DOI: 10.1016/s0968-0004(03)00171-3
Disciplines
  • Biology

Abstract

Abstract CHRD (after SWISSPROT abbreviation for chordin) is a novel domain identified in chordin, an inhibitor of bone morphogenetic proteins. Database searches have revealed several microbial homologues to this domain. It is anticipated to have an immunoglobulin-like β-barrel structure based on limited similarity to superoxide dismutases but, as yet, no clear functional prediction can be made.

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