The Danube-Kris-Mures-Tisa (DKMT) Euroregion has its roots back to 1992, when Timiş and Csongrád counties began the first discussions for a cross-border cooperation. Till 1997 the Euroregion needed to develop its institutions for greater effectiveness, so the period 1992-1997 could be considered a background of fruitful public and scientific discussions. The study is focused on three levels of developments: institutional-political, cultural and economical. It is a large reflection on the projects of which DKMT should profit in the future as well as on the economic potential of the Euroregion. The recent developments and the different stages of integration to the EU are also matters of discussions.