Affordable Access

Synthesis based on cyclohexadienes. Part 34. A tandem cationic rearrangement-ene cyclisation route to 2-pupukeanone

Royal Society of Chemistry
Publication Date
  • Organic Chemistry


A new strategy for the construction of the isotwistane skeleton is reported from easily available cyclohexadienes, which involves a one-pot cationic skeletal rearrangement and ene cyclisation of a bicyclo[2.2.2]octenone derivative and a cationic rearrangement of a tricyclo[,8)]decane to a [,7)]decane skeleton as the key steps in the synthesis of 2-pupukeanone.

There are no comments yet on this publication. Be the first to share your thoughts.