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Single bilayer liposomes prepared without sonication

Authors
Journal
Biochimica et Biophysica Acta (BBA) - Biomembranes
0005-2736
Publisher
Elsevier
Publication Date
Volume
298
Issue
4
Identifiers
DOI: 10.1016/0005-2736(73)90408-2

Abstract

Abstract Single bilayer liposomes, indistinguishable from those obtained by sonication, can be prepared by injecting an thanolic solution of phospholipid into water. The dilute suspension is easily concentrated by ultrafiltration and the mild conditions allow neither degradation nor oxidation of the phospholipid.

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