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Applanatines A–E from the culture broth ofGanoderma applanatum

Authors
Journal
Tetrahedron
0040-4020
Publisher
Elsevier
Publication Date
Volume
66
Issue
48
Identifiers
DOI: 10.1016/j.tet.2010.10.014

Abstract

Abstract Five novel compounds, applanatines A–E ( 1– 5), and a known one ( 6) were isolated from the culture broth of Ganoderma applanatum. Their structures including the relative configurations were determined by the interpretation of spectroscopic data. Compounds 3 and 4 suppressed the growth of Fusobacterium nucleatum, that is, a prominent member of the oral microflora implicated in periodontitis.

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