One of the problems with the implementation of a large scientific potential of Tomsk universities to modernize the Russian economy is the creation of enterprises capable of converting scientific research into a business, making a profit. The article, based on observation and expert interviews with the participants of one of the Tomsk business incubators, examines the experience of preparing teams of high-tech developers and entrepreneurs from the school. The process of preparation covered by a number of technological devices. These include the principles of creation of a business incubator, the motivation of its staff and volunteers, stages the selection of students who can lead the business of high technology, especially the age distance between mentors and clients, the structure of "think tank" and the relationship between the participants, the form and purpose of the interaction students with experienced entrepreneurs. Product of this new technology is the human mentality emerging business environment, consisting of current students and graduates. An important aspect of it is not only the desire to introduce new technologies, but also the formation of new relationships. The main value of the intellectual potential of human acts and the possibility of free and creative implementation.