Introduction Insomnia is a common condition that occurs in one third of the population, it can be associated with poor quality of life, anxiety, depression, impaired daytime functioning and chronic medication use. In addition headaches and difficulties in concentration occurs. Materials and methods We worked with 65 patients who had regular assistance during 8months, who had a diagnosis of chronic Insomnia with comorbidity; Depression, Anxiety, Personality disorder and Epilepsy. Polysomnography evidence of prolonged sleep latency was seen in most. Principal Symptoms of Mood disturbance, problems with memory and concentration, day time fatigue, stress and day time hypersommia were noted. The firststep was an specific interview with neurophycological tests evaluating memory, personality, anxiety and depression. The patients had a sleepdiary, according to the results they received individual therapy, also we worked support groups with differents topics like quality of life, stress management, relaxation, sleep hygiene, cognitive theraphy, sleep and sleep restriction. Results 80% of the patients got better with the combined therapy, improving the quality of life and the psycological problems, decreased use of chronic medication and night sleep condition greatly improved. Conclusion Behavioral and pharmacological therapy are effective in the management of chronic insomnia and improving sleep, helps to have a better quality of life. Acknowledgements Insomnia, behavior and cognitive treatment, quality of life.