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Survivor Curves for Leptospira autumnalis Akiyami A Based on Most-Probable-Number Values

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  • Clinical Microbiology And Immunology


The validity of survivor curves for Leptospira autumnalis Akiyami A based on most-probable-number values is supported by the following observations: (i) linear regression lines fell within most of the 95% confidence intervals; (ii) linear correlation coefficients (r) were consistently high (i.e., near -1); and (iii) statistical tests for goodness of fit usually accepted the linear model. These tests are consistent with an exponential death rate for the test organism in defined solutions. The influence of temperature and pH on survival was demonstrated by showing a statistically significant difference in survivor curve slopes.

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