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Solvent effects in capillary gas chromatography

Authors
Journal
Journal of Chromatography A
0021-9673
Publisher
Elsevier
Publication Date
Volume
279
Identifiers
DOI: 10.1016/s0021-9673(01)93621-0

Abstract

Abstract A survey of the effects of large amounts of solvent on peak shapes and retention times is given. Components with an elevated boiling point are spread in the column inlet by a flow of condensed solvent; their bands are broadened and distorted by “band broadening in space”. More volatile components are subject to “solvent trapping” effects, determined by their retention in the condensed solvent in the column inlet. “Phase soaking” is a solvent effect that occurs beyond the flooded inlet in the coated column and affects components eluted in the neighbourhood of the solvent or of a sample component that behaves similarly. In general, it tends to reconcentrate bands eluted after the solvent and to broaden those before the solvent.

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