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Dynamic instability of the major urinary protein gene family revealed by genomic and phenotypic comparisons between C57 and 129 strain mice.

Authors
  • 1
Type
Published Article
Publication Date
Volume
9
Issue
5
Identifiers
DOI: 10.1186/gb-2008-9-5-r91
PMID: 18507838
Source
Medline

Abstract

Our observations indicate that the MUP phenotypic polymorphism observed in wild populations results from a combination of Mup gene turnover coupled with currently unidentified mechanisms regulating gene expression patterns. We propose that the structural heterogeneity described within the cluster reflects functional divergence within the Mup gene family.

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