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C-erbB2 expression predicts response to preoperative chemotherapy for locally advanced breast cancer.

Authors
Type
Published Article
Journal
Anticancer research
Publication Date
Volume
18
Issue
5B
Pages
3695–3698
Identifiers
PMID: 9854479
Source
Medline

Abstract

This study has shown an increased likelihood of response to preoperative chemotherapy for breast cancers negative for c-erbB2 staining. Previous studies have shown that c-erbB2 immunostaining can correlate with either chemo-resistance or chemo-response. We postulate that this conflict may be due to differences in the type of chemotherapy administered. This raises the possibility of biological markers being use to assist in the selection of the type of chemotherapy regimen administered to particular tumour biological phenotype.

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