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Bronchogenic carcinoma of squamous cells in a young pregnant woman.

Authors
  • Penha, Daniel Silva Gontijo
  • Salge, Ana Karina Marques
  • Tironi, Fábio
  • Saldanha, João Carlos
  • Castro, Eumenia Costa da Cunha
  • Teixeira, Vicente de Paula Antunes
  • dos Reis, Marlene Antônia
Type
Published Article
Journal
Annals of Diagnostic Pathology
Publisher
Elsevier
Publication Date
Aug 01, 2006
Volume
10
Issue
4
Pages
235–238
Identifiers
PMID: 16844566
Source
Medline
License
Unknown

Abstract

Lung cancer continues to be the most incident neoplasia in the world and also the most frequent cause of death by cancer, with more than 900000 new cases per year. Women present greater risk of developing bronchogenic carcinoma, possibly because of differences in metabolism of the carcinogens associated with tobacco and also because of hormonal differences because estrogens can promote the appearance of lung cancer, including during pregnancy. We have described the case of a 25-year-old patient who developed squamous cell carcinoma of the lung during her third pregnancy, with a progressive worsening of her general condition and progression until death. We believe that the pregnancy could have contributed to the evolution of the disease, especially because of the increased levels of gestational hormones, particularly the estrogen, because its receptors have an important role in regulating growth and in the differentiation of several tissues facilitating like this, the development of the neoplasia, and complicating its early diagnosis.

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