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Broad spectrum detection of veterinary drugs with a highly stable metal-organic framework.

Authors
  • Wang, Bin1
  • Liu, Jing-Hao2
  • Yu, Jiamei3
  • Lv, Jie1
  • Dong, Chen1
  • Li, Jian-Rong4
  • 1 Beijing Key Laboratory for Green Catalysis and Separation, College of Environmental and Energy Engineering, Beijing University of Technology, Beijing 100124, PR China. , (China)
  • 2 College of Materials Science and Engineering, Beijing University of Technology, Beijing 100124, PR China. , (China)
  • 3 College of Materials Science and Engineering, Beijing University of Technology, Beijing 100124, PR China. Electronic address: [email protected] , (China)
  • 4 Beijing Key Laboratory for Green Catalysis and Separation, College of Environmental and Energy Engineering, Beijing University of Technology, Beijing 100124, PR China. Electronic address: [email protected] , (China)
Type
Published Article
Journal
Journal of hazardous materials
Publication Date
Jan 15, 2020
Volume
382
Pages
121018–121018
Identifiers
DOI: 10.1016/j.jhazmat.2019.121018
PMID: 31446354
Source
Medline
Keywords
Language
English
License
Unknown

Abstract

The broad spectrum detection of veterinary drugs is very important for rapid and large-scale safe screen of animal-derived foods. Metal-organic frameworks (MOFs), as a kind of emerged functional porous materials are quite promising in the chemical sensing and molecular detection. In this work, we report the high-performance broad spectrum detection of 15 commonly-used veterinary drugs through the fluorescence quenching in a newly-designed chemically stable Al-based MOF, Al3(μ3-O)(OH)(H2O)2(PPTTA)3/2 (BUT-22). To the best of our knowledge, this is the first systematic investigation for the application of MOFs in the detection/sensing of veterinary drugs through fluorescence quenching method. The quenching efficiencies of the tested veterinary drugs on BUT-22 are all beyond 82%, and the limits of detection (LOD) are low at parts per billion (ppb) levels. Interestingly, BUT-22 also enables the selective detection of nicarbazin (NIC) through the clearly-observed red shift of its maximum fluorescence emission wavelength. Moreover, the fluorescence quenching mechanism was explored with the help of theoretical calculations. Our work indicates that MOFs are favorable materials for the detection of veterinary drugs, being potentially useful in monitoring drug residues of animal-derived foods. Copyright © 2019 Elsevier B.V. All rights reserved.

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