College period is one of the most critical periods of one person’s life for it is an important period of establishing world concept, outlook on life and values. Various challenges and pressures have had a great impact on the mental health of college students. In that case, college students’ psychological confusion and mental health problems occur frequently and the overall condition of college students’ psychological problems is worrying. The mental health of college students has also attracted the attention of colleges and the society. Besides, the mental health education courses have been adopted to guide college students. This article aims to analyze the causes of college students’ psychological confusion and mental health problems and also the obstacles or difficulties in solving them from the perspective of college students' cultivation of positive psychological quality and mental health education. And corresponding solutions from both the outside and personal perspectives.