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Breakthrough in penicillin resistance? Streptococcus pneumoniae isolates with penicillin/cefotaxime MICs of 16 mg/L and their genotypic and geographical relatedness.

Authors
  • Soriano, Francisco
  • Cafini, Fabio
  • Aguilar, Lorenzo
  • Tarragó, David
  • Alou, Luis
  • Giménez, Maria-Jose
  • Gracia, Matilde
  • Ponte, Maria-Carmen
  • Leu, Denisa
  • Pana, Marina
  • Letowska, Iwona
  • Fenoll, Asuncion
Type
Published Article
Journal
Journal of Antimicrobial Chemotherapy
Publisher
Oxford University Press
Publication Date
Dec 01, 2008
Volume
62
Issue
6
Pages
1234–1240
Identifiers
DOI: 10.1093/jac/dkn392
PMID: 18799472
Source
Medline
License
Unknown

Abstract

The multidrug high resistance (precluding adequate oral therapy in children), its origin, the prevalence found in Romania and the presence of non-vaccine (7-valent) serotypes should worry the medical community because of a possible clonal diffusion that would limit therapeutic alternatives.

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