Cancer of the esophagus can metastasize to lymph nodes, lungs, liver etc. Brain accounts for less than 1% of cases. We encountered one unique case of carcinoma of esophagus who presented with brain secondaries as an initial manifestation. Cancer of the esophagus accounts for less than 1% of the cancers. Due to its inaccessible anatomical location, the diagnosis often gets delayed till late. Initially it tends to spread locally followed by metastasis to the lymph nodes and then to the distant organs. Distant metastasis per se is a relatively rare phenomenon, as locally advanced disease is a common cause of death.