Brain metabolite values in children with breath-holding spells.
Department of Pediatric Neurology.
Department of Radiology.
Department of Neurology.
Department of Pediatrics, Harran University School of Medicine.
Department of Pediatric Neurology, Eyyubiye Training and Research Hospital.
Department of Child and Adolescent Psychiatry, Harran University School of Medicine, Sanliurfa, Turkey.
- Published Article
Neuropsychiatric Disease and Treatment
Dove Medical Press
- Publication Date
Jan 01, 2017
Breath-holding spells are benign, paroxysmal events with apnea and postural tone changes after a crying episode in infants. The objective of this study was to investigate the pathologies in brain metabolite values in the absence of seizure in children with breath-holding spells by using magnetic resonance spectroscopy (MRS). Brain MRS examination was performed on 18 children with breath-holding spells and 13 neurologically normal children who were included as the control group. There was no significant difference in terms of N-acetyl aspartate (NAA), choline (Cho), creatine (Cr), and myoinositol (mI) levels and also in terms of NAA/Cr, Cho/Cr, and mI/Cr ratios between the patients and the control group (all P>0.05). Our study suggested that there is no permanent neuronal damage in patients with breath-holding spells. This result confirms the previous studies, which reported no permanent neuronal damage in patients with breath-holding spells.
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This record was last updated on 06/09/2018 and may not reflect the most current and accurate biomedical/scientific data available from NLM.
The corresponding record at NLM can be accessed at https://www.ncbi.nlm.nih.gov/pubmed/28721046