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Brain lesion in a recreational drug user: Isolated cerebral mucormycosis

Authors
  • Ha, Ngoc-Tram1
  • Lowery, Megan1
  • Woo, Jean2
  • Mehta, Yatin1
  • Bhanot, Nitin2
  • 1 Division of Pulmonary and Critical Care Medicine, Geisinger Medical Center, Danville, PA, 17882, United States
  • 2 Division of Infectious Disease, Allegheny General Hospital, Allegheny Health Network, PA 15212, United States
Type
Published Article
Journal
IDCases
Publisher
Elsevier
Publication Date
Oct 01, 2020
Volume
22
Identifiers
DOI: 10.1016/j.idcr.2020.e00979
PMID: 33083231
PMCID: PMC7554362
Source
PubMed Central
Keywords
License
Unknown

Abstract

Isolated cerebral mucormycosis is a relatively rare and unique variant of mucormycosis which is seen most commonly in patients with intravenous recreational drug use. While this invasive fungal infection in the brain is thought to spread from the sinuses or the lungs in other hosts such as diabetics and those with malignancy, hematogenous spread and seeding has been attributed in the pathogenesis of isolated cerebral mucormycosis. Clinical features and radiological findings may be non-specific and hence, heightened clinical suspicion for a prompt diagnosis and early medical and surgical intervention is paramount for a favorable outcome in such rare, but potentially fatal infections.

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