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Brain diffusivity in patients with neuropsychiatric systemic lupus erythematosus with new acute neurological symptoms.

Authors
  • Welsh, Robert C
  • Rahbar, Habib
  • Foerster, Bradley
  • Thurnher, Majda
  • Sundgren, Pia C
Type
Published Article
Journal
Journal of magnetic resonance imaging : JMRI
Publication Date
Sep 01, 2007
Volume
26
Issue
3
Pages
541–551
Identifiers
PMID: 17729344
Source
Medline
License
Unknown

Abstract

ADC histogram analysis demonstrated increased general diffusivity in the brain in NPSLE patients with acute symptoms compared with healthy normal controls. This finding suggests that in the brain parenchyma of NPSLE patients a loss of tissue integrity occurs facilitating motility of free-water protons.

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