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Bradykinin production during donor plasmapheresis procedures.

Authors
  • Perseghin, P
  • Capra, M
  • Baldini, V
  • Sciorelli, G
Type
Published Article
Journal
Vox sanguinis
Publication Date
Jul 01, 2001
Volume
81
Issue
1
Pages
24–28
Identifiers
PMID: 11520412
Source
Medline
License
Unknown

Abstract

Donors taking ACE inhibitors and undergoing plasmapheresis showed higher levels of BK compared to the control group. Furthermore, the detection of BK in plasma units after a freeze-thaw procedure might explain the sudden hypotensive reaction occurring during therapeutic plasma exchange when plasmapheresis units are adopted as substitution fluids. Further investigations are needed to assess the real clinical importance of the presence of BK in plasma units.

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