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Bowen’s Disease of the Nipple

Authors
  • Kitahara, Miyuki
  • Hozumi, Yasuo
  • Watanabe, Akie
  • Iijima, Tatsuo
Type
Published Article
Journal
Case Reports in Oncology
Publisher
S. Karger AG
Publication Date
Sep 07, 2018
Volume
11
Issue
3
Pages
609–614
Identifiers
DOI: 10.1159/000492382
PMID: 30323750
PMCID: PMC6180276
Source
Karger
Keywords
License
Green
External links

Abstract

Bowen’s disease is a type of intraepidermal squamous cell carcinoma that commonly develops in areas of the skin exposed to sunlight, such as the scalp, trunk, and limbs. Although development of Bowen’s disease in other sites, such as the nipple, is extremely rare, we herein report our experience with one such case. A 76-year-old female presented to our hospital with complaints of right nipple pruritus. We diagnosed Bowen’s disease via nipple skin biopsy, and the patient underwent right nipple resection. The deep tissue margin was positive for malignancy; therefore, the patient subsequently underwent right partial mastectomy. Histopathology revealed tumor cells inside the lactiferous ducts, but the resection margin was negative for malignancy. Bowen’s disease of the nipple may progress from the skin to the lactiferous ducts. Clinical findings can be used to evaluate lesion progression and determine the necessary extent of skin and mammary gland resection.

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