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Bovine submandibular gland extracts interact with the human hemostasis factors.

Authors
  • Menghi, G
  • Piciotti, D
  • Ravaglia, F
Type
Published Article
Journal
Cellular and molecular biology
Publication Date
Apr 01, 1992
Volume
38
Issue
2
Pages
151–158
Identifiers
PMID: 1571944
Source
Medline
License
Unknown

Abstract

Glycoconjugates were extracted from the bovine submandibular gland and their anticoagulant activity was tested on the blood coagulation of human beings. The methods employed demonstrated that the thromboelastographic parameters were only modified by the highest concentration of glycoconjugates. Activated Partial Thromboplastin Time (aPTT) and Thrombin Time (TT) were affected by dose-coupling response. Prothrombin Time (PT) and Reptilase Time (RT) were not modified.

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